Seminar Papers

[Article] Human neuroimaging reveals the subcomponents of grasping, reaching and pointing actions

Summary: This study shows us that the contributions of subcomponents of visuomotor activities have not been studied in detail (i.e., The contributions of subcomponents of visuomotor actions have not been explored in detail). Here, the Authors designed a Kinematic control experiment using hand. And they conducted selectivity analysis and compared it. They found/elucidated the different subcomponents of hand actions and the roles of specific brain regions in their computation.

Cavina-Pratesi, Cristiana, et al. “Human neuroimaging reveals the subcomponents of grasping, reaching and pointing actions.” Cortex 98 (2018): 128-148.

[Article] Linking Individual Differences in Personalized Functional Network Topography to Psychopathology in Youth

Summary: They utilized machine learning models to find associations between functional topography and four correlated dimensions of psychopathology and overall psychopathology (general psychopathology factor; p-factor).

Cui, Z., Pines, A. R., Larsen, B., Sydnor, V. J., Li, H., Adebimpe, A., … & Satterthwaite, T. D. (2021). Linking Individual Differences in Personalized Functional Network Topography to Psychopathology in Youth. bioRxiv.

[Article] Computational models of category-selective brain regions enable high-throughput tests of selectivity

Summary: A CNN model of the ventral stream was used to predict responses to the ROIs: FFA, PPA, and EBA. The model accurately predicted activations and the result was shown by synthesized stimuli using GAN. Moreover, they generated importance map for photographs where each ROI showed difference

Ratan Murty, N. A., Bashivan, P., Abate, A., DiCarlo, J. J., & Kanwisher, N. (2021). Computational models of category-selective brain regions enable high-throughput tests of selectivity. Nature communications, 12(1), 1-14.

[Article] The cortical network of emotion regulation: insights from advanced EEG-fMRI integration analysis.

Summary: This study uses their recently developed Spatio-temporal fMRI constrained EEG source imaging approach to perform source analysis on a simultaneous EEG-fMRI emotion regulation paradigm. They found cortical dynamics underlying negative emotional responses and reappraisal-based regulation using a newly developed multimodal EEG-fMRI integration technique. By using this method they could get detailed timecourses regional activities and causality analyses based on cortical current density could be identified.

Nguyen, Thinh, et al. “The cortical network of emotion regulation: insights from advanced EEG-fMRI integration analysis.” IEEE transactions on medical imaging 38.10 (2019): 2423-2433.

[Article] A framework for linking resting-state chronnectome/genome features in schizophrenia: a pilot study

Summary: They propose a novel framework to combine features corresponding to functional magnetic resonance imaging including dynamic functional network connectivity (dFNC) and SNP data from schizophrenia patients and healthy controls. For each subject, both the functional and SNP data are selected as features for a parallel ICA based imaging-genomic framework. They also assessed the correlations between the polygenic risk scores (PRS) and both dFNC and SNP components’ loading parameters.

Rashid, Barnaly, et al. “A framework for linking resting-state chronnectome/genome features in schizophrenia: a pilot study.” Neuroimage 184 (2019): 843-854.

[Article] Biomarker identification through integrating fmri and epigenetics

Summary: They combined linear regression with CCA in a coupled manner to extract discriminative features for schizophrenia that are co-expressed in the fMRI and DNA methylation data (epigenetic data).

Bai, Yuntong, et al. “Biomarker identification through integrating fmri and epigenetics.” IEEE transactions on Biomedical Engineering 67.4 (2019): 1186-1196.

[Article] Brain structure is linked to the association between family environment and behavioral problems in children in the ABCD study

Summary: In this article, they tried to find a relationship between family conflict, parental monitoring and children’s behavior problems and cognitive scores. They utilized sMRI, CBCL and KSADS to get 20 behavioral problems scores and 10 cognitive scores. They visualized correlation between these criteria and showed structural differences according to these scores. Furthermore, they performed longitudinal association analysis with baseline & 1 year later data. Utilizing CBCL scores into account in my study later seems reasonable.

Gong, et al. Brain structure is linked to the association between family environment and behavioral problems in children in the ABCD study. Nat Commun 12, 3769 (2021)

[Article] Learning patterns of the ageing brain in MRI using deep convolutional networks

Summary: Summary: In this paper, the authors predicted the brain age of T1-weighted MRI images in UK Biobank dataset using 3D CNN architecture. They examined the relationship between predicted ages and UK Biobank variables which are categorized into lifestyle factors (exercise, alcohol, tobacco, …), physiological/medical measurements (bone, cardiac, eye, …), and medical history. They adopted attention gates as attention modules to observe activation of the CNN model, and they also visualized the model using saliency map for comparison.

Dinsdale, Nicola K., et al. “Learning patterns of the ageing brain in MRI using deep convolutional networks.” Neuroimage 224 (2021): 117401.

[Article] Dynamic functional connectivity markers of objective trait mindfulness.

Summary: The goal of study is to identify the differences in dynamic functional connectivity according to the trait mindfulness. They found the high mindfulness trait group showed more strong within-network connectivity in the DMN and the salience network than the low mindfulness trait group.

Lim, J., Teng, J., Patanaik, A., Tandi, J., & Massar, S. A. (2018). Dynamic functional connectivity markers of objective trait mindfulness. NeuroImage, 176, 193-202.

[Article] Integrated 3D motion analysis with functional magnetic resonance neuroimaging to identify neural correlates of lower extremity movement.

Summary: Collected knee biomechanics.using an MRI-compatible motion capture system. The study shows promise for the MRI-compatible system to capture lower-extremity biomechanical data collected concurrently during fMRI, and the present data identified potentially unique neural drivers of aberrant biomechanics.

Anand, M., Diekfuss, J. A., Slutsky-Ganesh, A. B., Grooms, D. R., Bonnette, S., Foss, K. D. B., … & Myer, G. D. (2021). Integrated 3D motion analysis with functional magnetic resonance neuroimaging to identify neural correlates of lower extremity movement. Journal of Neuroscience Methods, 355, 109108.